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  • 名称:离体管状灌注浴槽系统

  • 型号:IPR
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简单介绍:
IPR(回肠) 用于回肠蠕动反射研究的水平组织浴槽系统
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灌注系统概述

HSEHA生理学系统是一系列应用广泛的完备产品,可用于整体动物生理学、立体或在体器官和组织灌注及组织浴槽研究。这些系统具有广泛的应用,包括传统的**药理学、DMPK、毒理学、呼吸系统、心脏病学、分子生物学和生理学。每个系统都设计了标准的组件,再加一些其他配置以适合特殊研究的需要。。标注组惨馕蹲湃绻闶切枰钟猩璞概淦耄蛘呓邢低成叮蛘呤峭暾呐涮撞罚愣贾恍枰郝蛐枰墓辜?/SPAN>HSE-HA生理学系统为你提供各种工具,使你的研究走向多产和成功。

我们提供大多数生理学检测设备,包括放大器、电极、传感器和电化学检测器。参数包括力、位移、压力、液体和气体流、心电图(单导联—12导联系统)、MAP(单个或多个部位)、脑电图、肌电图、连续支流灌注传统的血气参数和电解质的分析,可以选择程序化软件和传统的刺激器作为放大器、电极和传感器等产品的补充。

HSE-DAQ系统产品家族(BDASACADHAEMODYNISOHEARTPULMODYNPENNOCK)可以记录你的初始信号,计算到处的参数,注释数据,快速简易的输入确定的数据用于分析。同时还可以选择用于进一步分析的软件模块,带状记录纸打印,自动和控制模块等。产品经过预先设置,打开包装即可使用,并专门设计符合你的系统配置和数据分析要求。

 

Tissue Bath for Perfusing Ileum

• Basic test in gastrointestinal research

• Peristaltic reflex in guinea pig ileum

• For studying emptying phase of peristaltic reflex

 

This tissue bath has been designed for studying the peristaltic reflex in the guinea-pig ileum. The circular muscle contraction which propels the contents of the ileum from aboral to anal direction is induced by the increase of the intraluminal pressure up to a threshold point. The tissue bath is a water-jacketed Plexiglas bath. The holder for the cannulae can be removed from the main bath during the preparation. A 4 to 5 cm long segment of ileum, where the mesenteric has been removed and which has been flushed is cannulated in the oral and aboral ends and tided. Three different sizes of cannulae are available. The cannulae are fixed on sliding holders to optimize the distance between the cannulae and adapt to the individual length of the ileum avoiding any slackness of the tissue. The inflow is controlled by means of a peristaltic pump with a flowrate of about 0.5 ml/min. The direction of the perfusion flow must meet the physiological way. The outflow can be switched using a stopcock from a level equivalent to the level of the bath to a level of about 3 cm above the level of the fluid in the bath. The peristaltic reflex is induced by changing the position of the outflow stopcock. When it is in position ‘peristalsis’,  the pressure increases slowly resulting in a distention of the ileum until the pressure threshold level is reached. At this time the emptying phase is started as a visible contraction of the circular muscle moving from the oral to the aboral side.

The intraluminal pressure is recorded from the oral side by a pressure transducer and the appropriated amplifier and recorder. The pressure transducer must be sensitive enough to reproduce the small threshold point of 1 to 2 cmH2O

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