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首页 >>> 产品目录 >>> 多肽合成仪
产品[AAPPTEC平行合成仪]资料
如果您对该产品感兴趣的话,可以
产品名称: AAPPTEC平行合成仪
产品型号: Apex 396
产品展商: Aapptec
简单介绍
Apex 396平行合成仪是美国老牌多肽合成仪制造商AAPPTEC公司的成熟产品。美国AAPTEC公司在全球多肽领域拥有领先的科技,经过近30年的发展,产品系列丰富合理,从单到多通道多肽合成仪质量可靠,应用便捷满足不同客户的需求,全球已经有近万台我们的产品在正常运行。Apex 396平行合成仪能够胜任液体,固相多肽以及有机合成反应,具备多通道反应器,自然基因科技拥有经过厂家培训的专业技术人员。
AAPPTEC平行合成仪的详细介绍


 



美国AAPPTec公司

Apex 396平行合成仪

全自动多功能多肽合成仪



Apex 396平行合成仪,也称396多功能多肽合成仪是目前世界上平行多肽合成和单通道多肽合成仪的市场领袖。Apex 396平行合成仪是作为生产药物研发库、丙氨酸扫描alanine scans、抗原表位定位和多肽平行试验库的理想仪器。合成规模从15毫克到2克。

高产量:

由于特氟龙反应器的独特设计,树脂停留在反应器底部,可以充分接触反应溶剂。基于这一点,树脂不会粘在反应器的边缘,因此Apex 396平行合成仪能够生产出更高产量的高纯度多肽。

高效率:

当维持一个惰性化境时,大气氮气辅助底部过滤能快速和彻底地排清反应器,结果就是快速清空。这个处理,结合快速输送,最小化多肽树脂分解应归于延长和酸的接触或者高效率彻底的清洗树脂以防止杂质转移。

高质量:

这些特性与优点使得Apex 396平行合成仪成为全自动环境温度平行多肽合成仪的**选择。








 

Apex 396平行合成仪是一个易于使用的自动化液体处理系统,能够胜任对液态、固相肽合成和有机合成反应。所有试剂、反应容器均在铝合金密封舱里,因此无需额外的通风橱设备。




Apex 396平行合成仪支持多达96个化合物可以在四氟乙烯块内同时合成,同时也可以在40孔、16孔和8孔模式中选择合成。

Apex 396平行合成仪在96孔反应模式下,合成时间平均为30摩尔肽,每个肽20分钟。依据化学合成过程,氨基酸循环累加时间范围从45分钟到1.5个小时。




Apex 396平行合成仪同轴喷雾探头传输溶剂精确度达到了0.5毫升。同轴探头有两个通道:用于溶剂和其他用于惰性气体(氮气或者氩气)。在溶剂送气过程中排出的溶剂替换为惰性气体;在溶剂传输过程中,气体保持贯彻整个合成。探头还负责液体的检测,通过鉴定测量溶剂的电容率。这可确保探头进入液面一下的溶剂,探头接触减少可减少宝贵样品之间的交叉污染。

Apex 396平行合成仪反应容器通过正压的氮气压力被清除干净,保持一种惰性环境并确保能有效去除容器底部的所溶剂和试剂。

Apex 396平行合成仪范围有四种模式:

Apex 396-SC: 单臂和经典反应器
Apex 396-DC: 双臂和经典反应器
Apex 396-DC-FW-S: 双臂系统,经典反应器,快洗功能和第二臂单针探头
Apex 396-DC-FW-M: 双臂系统,经典反应器,快洗功能和第二臂多针探头

Apex 396平行合成仪基于其可靠性、耐用性、易用性和高性能。高品质的纯钛可以容易和快速的合成。所有类型的肽和有机化学反应都可以在这个高度灵活的桌面单元操作。

主要特点
 
• 多种肽合成执行液体和固相化学合成
• 1-96化合物可同时合成
• 多种氨基酸和反应容器配置
• 桌面多肽合成
• 全封闭罩,包含烟雾和有害气味
• 模式桌面试剂放置允许较大的灵活性
• 自动切割FMOC-化学
• 稀释器/注射器配药系统微升精度
• 双臂机器人可利用单或多探头在第二臂上

主要技术参数:

• 可变规模合成
• 变速漩涡混合反应块,300-1200转/分钟
• 聚四氟乙烯不粘表面和惰性环境反应器
• 样品过滤聚四氟乙烯反应器熔块
• 隔垫反应孔维持压,防止交叉污染,并减少溶剂损失
• 铝制模式桌面允许灵活的试剂位置
• 多达6大部分外部溶剂线
• 350毫升和800毫升的试剂瓶
• 两个溶剂试剂稀释器在第一个手臂上(在所有APEX型号)
• 用于来自稀释器的溶剂输送齿轮泵
• 精确的溶剂输送直到0.5升
• 同轴喷雾探头用于溶剂输送和液体检测
• 探头清洗站,以防止交叉污染
• 辅助氮正压力容器在不到1分钟排空
• 氮和溶剂的检测系统,以防止在试剂缺乏的情况下操作
• 快速请洗功能,在双臂的Apex型号,在96反应孔1-1.5分钟
• 直观的易于使用和编程简单的软件,指向和点击命令

主要选项:

可选配件:
聚四氟乙烯反应孔:96,40,16和8

• 树脂分配器:35毫克或70毫克可用
• 单体架:4x9架使用35毫升瓶,8X12架使用10毫升瓶,
          2X5架使用25毫升瓶,5X6架使用125毫升瓶装。
          可定制机架。
    酶标块96孔板的送样
    样品的沉积、树脂切割,适用于96×4 ml样品瓶,40×6毫升小瓶,16×15毫升的小瓶和8×35毫升小瓶


灵活性:

*  Apex 396平行合成仪既可以生产单个肽,也可以同时生产少量肽或者较高同时
   生产96个肽。
*  双机器人臂精准的在任意两个点之间传输试剂。
*  密封罩内可以灵活地使用任何形状,尺寸或者放置容器
*  Apex 396平行合成仪可以灵活的支持任何化学类型,包括预激活氨基酸




混合模式:



* Apex 396平行合成仪具备柔和但是高效的涡旋混合可以完全混合树脂和试剂
* Apex 396平行合成仪涡旋混合提供了高度的一致性和持续性,保障了高质量高纯肽和蛋白质的生产。



Apex 396平行合成仪是当今市场上顶级的多肽合成仪。



Apex 396平行合成仪附件与部件列表  

Reaction and Cleavage Assemblies

反应与切割部件
Catalog Number
货号
Part
部件
Description
描述
101476 96 Vessel Classic Reactor Assembly 96 two ml reactor assembly for preparing up to 96 different products simultaneously. 
100018 96 Vessel Top Clamp Plate Top clamping plate for 96 Vessel Classic Reactor Assembly
99000101 96 Vessel Classic Cleavage Assembly Use with the 96 Vessel Reactor Assembly to cleave products from resin in 96 reactors and collect the products in 4 ml glass vials.  Glass vials included.
99001301 40 Vessel Classic Reactor Assembly 40 five ml reactor assembly for preparing up to 40 different products simultaneously. 
102245 40 Vessel Top Clamp Plate Top clamping plate for 40 Vessel Classic Reactor Assembly
10241001 40 Vessel Classic Cleavage Assembly Use with the 40 Vessel Classic Reactor Assembly to cleave products from resin in 40 reactors and collect the products in 6 ml glass vials.  Glass vials included.
99001701 16 Vessel Classic Reactor Assembly 16 ten ml reactor assembly for preparing up to 16 different products simultaneously. 
10238503 16 Vessel Top Clamp Plate Top clamping plate for 16 Vessel Classic Reactor Assembly
990008 16 Vessel Classic Cleavage Assembly Use with the 16 Vessel Classic Reactor Assembly to cleave products from resin in 16 reactors and collect the products in 15 ml glass beakers.  Glass beakers included.
99003501 8 Vessel Classic Reactor Assembly 8 twenty ml reactor assembly for preparing up to 8 different products simultaneously.
101249 8 Vessel Top Clamp Plate Top clamping plate for 8 Vessel Classic Reactor Assembly
990026 8 Vessel Classic Cleavage Assembly Use with the 8 Vessel Classic Reactor Assembly to cleave products from resin in 8 reactors and collect the products in 35 ml glass beakers.  Glass beakers included
10002401 Septa for Reactor Assembly Top Plate Use with all Classic Reactor Assemblies
10221301 Frits, Coarse, for 96 Vessel Classic Reactor Assembly  Replacement frits for 96 vessel Classic Reactor assemblies
260062 Frits for 96 and 16 Vessel Classic Reactor Assemblies Replacement frits for 96 and 16 vessel Classic Reactor assemblies
10223401 Frits for 40 and 8 Vessel Classic Reactor Assemblies Replacement frits for 40 and 8 vessel Classic Reactor assemblies.
250946 Silicon Plugs for 96 and 16 Vessel Classic Reactor Assemblies Silicon plugs to plug unused vessels within an active zone in 96 and 16 vessel Classic reactor assemblies.
260166 Silicon Plugs for 40 and 8 Vessel Classic Reactor Assemblies Silicon plugs to plug unused vessels within an active zone in 40 and 8 vessel Classic reactor assemblies.
10002501 O-Ring, Reactor and Cleavage Assemblies O-Ring for Classic reactor and cleavage assemblies.
10002601 O-Ring, N2Pins O-ring that fits over the N2 pin in Classic reactor assemblies
950225 Resin Dispenser, 96 Vessel, 50 mg per vessel Simultaneously dispenses 50 mg of resin to each vessel of a 96 vessel Classic reactor or 96 vessel Ares reactor.
950418 Resin Dispenser, 40 Vessel, 35 mg per vessel Simultaneously dispenses 35 mg of resin to each vessel of a 40 vessel Classic reactor .
950251 Resin Dispenser, 96 Vessel, 25 mg per vessel Simultaneously dispenses 25 mg of resin to each vessel of a 96 vessel Classic reactor or 96 vessel Ares reactor.

 

Monomer Racks零件

Part Number Part Description
950165 4 x 9 Monomer Rack Assembly Rack contains 36 monomer bottles; each monomer bottle holds 35 mL.
10008801 35 mL Monomer Bottle (with cap) Fits 4 x 9 Monomer Rack
10009301 Cap with Hole for 35 mL Monomer Bottle Used with Septum 260237
10053001 Cap without Hole for 35 mL Monomer Bottle  
260237 Septa For 35 mL Monomer Bottles
95001101 8 x 16 Monomer Rack Assembly Rack contains 124 monomer bottles; each monomer bottle holds 10 mL.
10083001 10 mL Monomer Bottle (with cap) Fits 8 x 16 Monomer Rack and 8 x 12 Monomer Rack
10139801 Cap with Hole for 10 mL Monomer Bottle Used with Septum 101396
101396 Septa For 10 mL Monomer Bottles
950169 8 x 12 Monomer Rack Assembly Rack contains 96 monomer bottles; each bottle holds 10 mL
950166 2 x 5 Monomer Rack Assembly Rack contains 10 monomer bottles; each monomer bottle holds 125 ml.
10139701 125 mL Monomer Bottle (with cap with hole) Fits 2 x 5 Monomer Rack
10139501 Septa For 125 mL Monomer Bottles
950043 18 - 18 Monomer Rack Assembly Rack contains eighteen 30 mL bottles and eighteen 10 mL bottles. 
32000501 30 mL Monomer Bottle for 18 - 18 Monomer Rack 30 mL monomer bottle (29 x 82mm) for 18 - 18 Monomer Rack.
32000601 10 mL Monomer Bottle for 18 - 18 Monomer Rack 10 mL monomer bottle (24 x 72mm) for 18 - 18 Monomer Rack.
980110 5 x 6 Monomer Rack Assembly Rack holds 30 monomer bottles (950407); each bottle holds 125 mL
980111 5 x 5 Monomer Rack Assembly Rack holds 25 monomer bottles (950407); each bottle holds 125 mL.
980112 5 x 4 Monomer Rack Assembly Rack holds 20 monomer bottles (950407); each bottle holds 125 mL
980112 5 x 1 Monomer Rack Assembly Rack holds 5 monomer bottles (950407); each bottle holds 125 mL
950407 125 mL Monomer Bottles 125 mL Monomer bottles with septa.

 

Reagent Bottles反应瓶

Part Number
货号
Part
部件
Description
描述
10009101 300 mL Reagent Bottle Glass reagent bottle, with P/N 250881, fits on the tabletop of Apex 396
250881 Base for 300 mL Reagent Bottle Base for P/N 100091, fits on the tabletop of Apex 396
990299 800 mL Reagent Bottle (with stand) Larger reagent bottle for frequently used reagents and/or reagents used in larger quantities.  Fits on the tabletop of Apex 396.
320053 800 mL Oblong Reagent Bottle Larger reagent bottle for frequently used reagents and/or reagents used in larger quantities.  Fits on the tabletop of Apex 396.
260237 Septa Septa for 300 mL and 800 mL Reagent Bottles
260032 Lead Vinyl Ring For 300 mL and 800 mL Reagent Bottles

 

Parts部件

Part Number
     货号
Description
  描述
950370 Spray Probe
250299 4.1" Coaxial Probe for Multiprobe
250298 4.0" Coaxial Probe for Multiprobe
10074401 Diluter Valve
101376 Grommet, 10 mL Syringe Overrun Protection 
260093 Syringe, 5 mL for Diluter
260251 Syringe, 10 mL for Diluter
10003902 Stainless Steel System Fluid Filter (Requires 10087201)
10087201 System Fluid Filter Adapter (Requires 10003902)
10050001 Isolation Block
100500A2 Isolation Block with Hole for Coaxial Probe
25005001 Ferrule for Coaxial Probe
106095 Fuse, 2X10 Amp Type T, 120V
106069 Fuse, 2X6.3 Amp Type T, 240V
Apex 396平行合成仪是发表文献最多的多肽合成仪

 


关于美国AAPPTEC公司:



美国AAPPTEC公司,英文全称为Advanced Automated Peptide Protein Technologies公司,即美国先进自动多肽蛋白技术公司成立于2005年3月,公司的前身是ACT(Advanced ChemTech)公司的仪器部。AAPPTEC公司购买了前ACT公司仪器的全部资产,包括生产线,专利权以及在生产、促销和服务等方面的独家特权。AAPPTEC公司投入了充足的资源去提升和改进设备生产线,与此同时为药学界和生物领域提供了众多创新性新产品。

AAPPTEC公司极其前身一直由Hossain Saneii博士来管理和运作整个公司,其总部设在美国肯塔吉州的路易斯维尔。近20年里,AAPPTEC公司在全自动多肽合成仪领域,针对不同的需求研发出数十种类型的仪器,加上长期实际应用验证的可靠性,这些仪器均可满足不同客户的不同需求,而且使用起来都相当便利,得到了全球用户的一致好评。AAPPTEC公司的多肽合成仪一定会满足您的需要,无论从仪器本身,到合成技术,到售后服务,我们在美国的工程师以及中国本土的高水平科学工作者也会一如既往地为您提供专业、周到的服务。

* 自然基因科技自2012年9月开始总代理美国AAPPTEC公司的产品。*



本产品提供1年全免费售后服务,包括产品介绍、送货、安装、调试、维修、技术培训服务等(与客户有特殊约定的按照约定执行)。
我们的标准服务流程为:
l 仪器完好无损运送到客户处
l 专业工程师接到派工单,与客户主动联系:了解客户现场情况、告知客户需要准备的必要条件、与客户约定安装培训时间
l 专业工程师到达客户现场,向客户主动出示工作证件和安装培训执照
l 专业工程师检查货物包装情况,按照合同与客户一起清点货物
l 在客户指定的符合仪器运行条件的位置,安装仪器
l 测试电压并开机试运行仪器
l 向客户介绍各个硬件组成部分
l 向客户介绍仪器的硬件操作
l 培训客户使用软件
l 向客户告知仪器运行注意事项与保养规则
l 回答客户疑问
l 陪同客户试用仪器
l 与客户一起签署工作报告、保修单与验收报告
l 将服务联系标牌贴在醒目位置,便于客户联系工程师
l 2-4周后回访客户,并解答客户提出的在使用中出现的问题
尊重客户,理解客户,一切从客户角度出发,持续提供超越客户期望的产品与服务,做客户们永远的伙伴。这是我们一直坚持和倡导的服务理念。
l 心中永远首先想到的是客户,我们提到的质量不仅仅指产品的内在质量,还包括产品的包装质量、服务质量等一系列因素。因此必须全面地、较大限度地满足客户的需求。
l 应站在客户的立场,而不是站在公司的立场上去研究、设计和改进服务。
l 完善服务系统,加强售前、售中、售后服务,对客户在使用中出现的各种问题及时帮助解决,使客户感到极大方便。
l 高度重视客户意见,把处理客户的意见作为使顾客满意的重要一环。
l 5S理念:“5S”是指“微笑(SMILE)、迅速(SPEED)、诚实(SINCERITY)、灵巧(SMART)、研究(STUDY)”五个词语英文首字母的缩写。“5S”理念是颇具代表性的服务文化创新,不仅具有人性化十足的时代特点,还具备相当的可操作性。
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厂家产品链接:http://www.aapptec.com/custdocs/FocusXC%202_doc.pdf?osCsid=iilgldhkggg8t7eddr006ddq91



附录:参考文献---谁在使用这台仪器?


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